• It is a chemically synthesised highly hydrophilic macromolecular compound with a bondable group.
• Inhibits non-specific adsorption of proteins by forming a dense hydrophilic layer at the site to be blocked, and improves the activity of the coupling agent. They can be covalently bound to solid phase surfaces containing carboxyl groups and other groups. In addition, oligoammonia short chains have a small positive charge and can be adsorbed on negatively charged solid phase surfaces or proteins by electrostatic interaction. Also, they can be used to improve the dispersion stability of colloidal gold particles by utilising the ligand binding of unshared electron pairs. In the application of immunodiagnostic reagents can make up for the shortcomings of the conventional sealer BSA, and can be used instead of BSA or in combination with BSA.
• The use of this series of sealers for closure helps the antibody to maintain the correct stereo conformation, maintaining the activity of the antibody and thus obtaining the effect of a stronger signal. In addition, the hydrophilicity and occupancy effect of PEG in the polymer can effectively reduce the reagent background.